Self Quiz for Viral Activation of Immune Responses

Study the material in this section and then write out the answers to these questions.
 Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. An antigen-nonspecific defense mechanisms that a host uses immediately or within several hours after exposure to almost any microbe. This is the immunity one is born with and is the initial response by the body to eliminate microbes and prevent infection. This best describes which? 

 A. adaptive immunity 

 B. cell-mediated immunity 

C. humoral immunity 

D. innate immunity   (ans)

2. An antigen-specific defense mechanisms that take several days to become protective and are designed to react with and remove a specific antigen. This is the immunity one develops throughout life. This best describes which? 

A. adaptive immunity

B. innate immunity (ans)

3. The actual portions or fragments of an antigen that react with antibodies and with receptors on B-lymphocytes and T-lymphocytes are called ____________.

A. PAMPs

B. PRRs

C. epitopes

D. antibodies (ans)

4. The production of antibody molecules in response to an antigen and mediated by B-lymphocytes best describes which?

A. innate immunity

B. cell-mediated immunity

C. humoral immunity (ans)

5. How do antibodies protect against viruses? [mark all correct answers]

A. The Fab portion of the antibody binds to viral surface antigens and blocks adsorption to host cell receptors. The Fab portion of the antibody binds to viral surface antigens and blocks adsorption to host cell receptors.

B. The Fab portion of the antibody binds to viruses and the Fc portion sticks the virus to cytotoxicT-lymphocytes (CTLs) to induce apoptosis.

C. The Fab portion of the antibody binds to the binding portion of viral exotoxins and blocks their attachment to host cell receptors.

D. The Fab portion of the antibody binds to viral epitopes and the Fc portion binds to phagocytes to promote opsonization.

E. The Fab portion of the antibody binds to virus and the Fc portion activates the complement pathways to produce interferons. (ans)

6. CTLs use the _____________ on their surface to bind to ____________ on infected cells and tumor cells.

A. MHC-I molecules with bound peptide epitopes from viral antigens; TCRs and CD8 molecules

B. TCRs and CD8 molecules; MHC-I molecules with bound peptide epitopes from viral antigens

C. TCRs and CD4 molecules; MHC-II molecules with bound peptide epitopes from viral antigens

D. MHC-II molecules with bound peptide epitopes from viral antigens; TCRs and CD4 molecules (ans)

7. An immune response that does not involve antibodies but rather involves the activation of macrophages and NK-cells, the production of antigen-specific cytotoxicT-lymphocytes is called what?

A. humoral immunity

B. cell-mediated immunity

C. innate immunity

D. hypersensitivity (ans)

8. NK cells use the _____________ on their surface to bind to ____________ on infected cells and tumor cells.

A. killer-inhibitory receptors; stress glycoproteins

B. TCRs and CD8 molecules; MHC-I molecules with bound peptide epitopes from viral antigens

C. killer-activating receptors; stress glycoproteins

D. MHC-II molecules with bound peptide epitopes from viral antigens; TCRs and CD4 molecules (ans)


 

Gary E. Kaiser, Ph.D.
Professor of Microbiology
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work The Grapes of Staph at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Creative Commons License

Last updated: Feb., 2020
Please send comments and inquiries to Dr. Gary Kaiser